My two favorite PICO's



1.  The Puma PICO





2.  PICO #2:  "For a 40-year old, Caucasian female with bipolar disorder, is electroconvulsive therapy more effective than lithium for reducing hallucinations?"

Patient =          40-yr old, Caucasian female

Problem =        Bipolar disorder

Intervention =  Electroconvulsive therapy

Comparison =  Lithium

Why?  Is it a good PICO.  Cuz it's all MeSH...no plebeian keywords allowed here.  4 solid parts of controlled vocabulary goodness that is saving Princess Leia...

Carrie Fisher spiraled into the worst depression of her life after a close friend died in 2005. "I was as close to being suicidal as you can be without being suicidal," said the 55-year-old actress, novelist, and Star Wars legend. "I was devastated." When anti-depressants and psychotherapy failed to help, she turned to ECT. "Over time, this f---ing thing punched the dark lights out of my depression," she said. "It was like a mute button muffling the noise of my shrieking feelings." Now she's come to depend on shock treatments every six weeks to keep her demons at bay, though she says the cure can be "a bitch on memory." ECT's most common side effect, temporary memory loss, does have an upside, she said. She forgets movies she's just seen, but now "I can be entertained by them all over again."  --Source "The Week"