Yea MeSH can be hard, so is going to college, having children, and a slew of other worthwhile activities.
|"You can't always get what you want, but if you try sometime, you just might find, you get what you need." --Jagger/Richards|
It's preposterous that someone in bioinformatics would claim to be "so over MeSH." For advanced users, researchers, and librarians, MeSH is an absolute must.